and sensitive enough to detect and quantify endogenous levels of oxidative stress on proteome-wide scale and brings a new perspective on the role of the modification site occupancy in cellular redox response.īauxite mining and alumina refining: process description and occupational health risks.ĭonoghue, A Michael Frisch, Neale Olney, David Quantitative information allowed us to determine relative modification site occupancy of each identified modified residue and pin point heavily modified ones. Only 6 modified peptides changed significantly under mild oxidative stress. On the other hand residues with low modification level can be dramatically affected by mild oxidative imbalance. We show that, on one hand, heavily modified cysteines are not necessarily involved in the response to oxidative stress. Rogowska-Wrzesinska, Adelina Wojdyla, Katarzyna Williamson, James
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